50. Kenny, R.; Liu, F.*

Asian Journal of Organic Chemistry 2022, in press.

Robust and Scalable Synthesis of Soai Aldehydes via Improved Barbier-type Halogen–lithium Exchange

49. Liu, F.;*Sameem, B.

Targets in Heterocyclic Systems 2021,502-516.

Fluorinated N-heterocycles as conformationally diverse bioactives for drug discovery

48. Santos, J.; Dolai, S.; O'Rourke, M. B.; Liu, F.; Padula, M. P.; Molloy, M. P.; Milthorpe, B. K.*

Int. J. Mol. Sci. 2021,160.

Quantitative Proteomic Profiling of Small Molecule Treated Mesenchymal Stem Cells Using Chemical Probes

47. Eliseenko, S.; Bhadbhade, M. M.; Liu, F.*

Chirality, 2020, 1311-1323.  

Multifunctional chiral aminophosphines for enantiodivergent catalysis in a palladium-catalyzed allylic alkylation reaction

46. Barua, P.; Ahn, S. B.; Mohamedali, A.; Liu, F.*

Biotech Lett, 2020, 683-695.

Improved sensitivity in cell surface protein detection by combining chemical labeling with mechanical lysis in a colorectal cancer cell model

45. Hardianto, A.; Yusuf, M. Liu, F.; Ranganathan, S.*

Encyclopedia of Bioinformatics and Computational Biology, 2019, 273-282.

Structure-Based Drug Design Workflow

44. Liu, M.; Karuso, P.; Feng, Y.; Kellenberger, E.; Liu, F.; Wang, C.; Quinn, R. J.*

ChemMedComm, 2019, 1659-1846.

Is It Time for Artificial Intelligence to Predict the Function of Natural Products Based on 2D-Structure

43. Gotsbacher, M. P.; Cho, S. M.; Kim, N. H.; Liu, F.; Kwon, H. J.; Karuso, P.*

ACS Chemical Biology, 2019, 636-643.  (Highlighted in ACS C&EN News, 2019)

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate

42. Eliseenko, S.; Liu, F.*

Tetrahedron, 2019, 518-526.  

Switchable Pyrrole-based Hydrogen Bonding Motif in Enantioselective Trifunctional Organocatalysis

 

41. Hardianto, A.; Khanna, V. Liu, F.; Ranganathan, S.*

BMC Bioinformatics 2019, 19 (Suppl 13):342

Diverse dynamics features of novel protein kinase C (PKC) isozymes determine the selectivity of a fluorinated balanol analogue for PKCε

40. Moore, A. F.; Newman, D. J.; Ranganathan, S.; Liu, F.*

Australian Journal of Chemistry, 2018, 917-930.  

Imaginative Order from Reasonable Chaos: Conformation- Driven Activity and Reactivity in Exploring Protein–Ligand Interactions 

39. Hardianto, A.; Liu, F.; Ranganathan, S.* 

Journal of Chemical Information and Modeling, 2018, 511-519.  

Molecular Dynamics Pinpoint the Global Fluorine Effect in Balanoid Binding to PKCϵ and PKA

38. Spedding, H.; Karuso, P.; Liu, F.*

Molecules 2017, 1871-1887. 

Synthesis of substituted Oxo-Azepines by regio - and diastereoselective Hydroxylation 

37. Ari, Hardianto.; Liu, F.; Ranganathan, S.*

BMC Bioinformatics 2017, Suppl 16, p. 19-30 12 p., 572.

Exploration of charges states of balanol analogues acting as ATP mimics in kinases.

36. Patel, A.; Ari, Hardianto.; Ranganathan, S; Liu, F.*

Organic & Biomolecular Chemistry 2017, 1570-1574.

Divergent response of homologous ATP sites to stereospecific ligand fluorination for selectivity enhancement.

35. Kenny, R.; Liu, F.*

Chemical Record 2017, 535-553.

Cooperative Trifunctional Organocatalysts for Proficient Proton Transfer Reactions.

34. Liu, F.;* Koval, M.; Ranganathan, S.; Fanayan, S.; Hancock, W.; Lundberg, E.;, Beavis, R.; Lane, L.; Duek, P.; McQuade, L.; Kelleher, N.; Baker, M.
Journal of Proteome Research 2016, 339-59.
Systems Proteomics View of the Endogenous Human Claudin Protein Family.

33. Patel, A.; Bhadbhade, M.; Liu, F.*
Acta Crystallographic Communications E 2015, E71, 1361-65.
Crystal structure of (4R,5S,6R)-6-azido-5-benzyloxy-3,3,4-trifluoroazepan-1-ium 2,2,2-trifluoroacetate from synchrotron data.

32. Kenny, R.; Liu, F.*
European Journal of Organic Chemistry 2015, 5304-19.
Trifunctional Organocatalysts: Catalytic Proficiency by Cooperative Activation Trifunctional Organocatalysts: Catalytic Proficiency by Cooperative Activation.

31. Patel, A.; Liu, F.*
Australian Journal of Organic Chemistry 2015, 50-60.
Cooperative Conformational Regulation in N-Heterocyclic Fluorohydrins.

30. Patel, A.; Hunter, L.; Bhadbhade, M. M.; Liu, F.*
European Journal of Organic Chemistry 2014, 2584-2593.
Conformational Regulation of Substituted Azepanes through Mono-, Di-, and Trifluorination.

29. Prediction of the Repeat Domain Structures and Impact of ParkinsonismAssociated Variations on Structure and Function of all Functional Domains of LeucineRich Repeat Kinase 2 (LRRK2) Mills, R. D.; Mulhern, T. D.;Liu, F.; Culvenor, J. G.; Cheng, H-C.*
Human Mutation 2014, 395-412.
Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2).

28. Liu, F.
Chirality 2013, 675-683.
The upside of downsizing: asymmetric trifunctional organocatalysts as small enzyme mimics for cooperative enhancement of both rate and enantioselectivity with regulation.

27. Patel, A.; Ball, G.; Hunter, L.; Liu, F.*
Organic & Biomolecular Chemistry 2013, 3781-3785.
Conformational regulation of substituted azepanes through selective monofluorination.

26. Anstiss, C.; Karuso, P.; Richardson, M.; Liu, F.*
Molecules 2013, 18, 2788-2802.
Synthesis of new BINAP-based aminophosphines and their 31P-NMR spectroscopy.

25. Patel, A.; Liu, F.*
Tetrahedron 2013, 69, 744-752
Diastereospecific fluorination of substituted azepanes. 

24. McRae, C.; Karuos, P.; Liu, F.*
Journal of Chemical Education 2012, 89, 878-883
ChemVoyage: a web-based, simulated learning environment with scaffolding and linking visualization to conceptualization.

23. Dolai, S.; Xu, M.; Liu, F.; Molloy, M.*
Proteomics 2011, 8, 2683-2693.
Quantitative chemical proteomics in small scale culture of phorbol ester stimulated basal breast cancer cells.

22.  Anstiss, C.; Garnier, J-M.; Liu, F.*
Organic & Biomolecular Chemistry 2010, 8, 4400-4407.
Mechanistic investigations of multidentate organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita-Baylis-Hillman reactions are ambient temperature.

21. Anstiss, C.; Liu, F.*
Tetrahedron 2010, 66, 5486-5491. 
Cooperativity in the counterion catalysis of Morita-Baylis-Hillman reactions promoted by trifunctional Organocatalyst. 

20.  Garnier, J-M.; Liu, F.*
Organic & Biomolcular Chemistry 2009, 1272-1275.
Trifunctional Organocatalyst Promoted Counterion Catalysis for Fast and Enantioselective aza-Morita-Baylis-Hillman Reactions at Ambient Temperature. 

19.  Garnier, J-M.; Anstiss, C.; Liu, F.*
Advanced Synthesis & Catalysis 2009, 351, 331-338. (Highlighted in Synfacts 2009, 4, 447)
Enantioselective Trifunctional Organocatalysts for Rate-Enhanced Aza-Morita–Baylis–Hillman Reactions at Room Temperature. 

18. Stephens, B. E.; Liu, F.*
Journal of Organic Chemistry 2009, 74, 254-263.
A Regio- and Diastereoselective Intramolecular Nitrone Cycloaddition for Practical 3- and 2,3-Substituted Piperidine Synthesis from gamma-Butyrolactone. 

17. Patil, S. N.; Stephens, B. E.; Liu, F.*
Tetrahedron  2008, 73, 10831-10836.
A tandem Baylis-Hillman-singlet oxygen oxidation reaction for facile synthesis of gamma-substituted gamma-hydroxybutenolides. 
 
16. Patil, S. N.; Liu, F.*
Journal of Organic Chemistry  2008, 73, 4476-4484.
Regioselective Synthesis and Structural Studies of Substituted gamma-Hydroxybutenolides using a Tandem Baylis-Hillman/Singlet Oxygenation Reaction.

15. Patil, S. N.; Liu, F.*
Journal of Organic Chemistry  2007, 72, 6305-6308.
Fluoride-Assisted Regioselective Conversion of Functionalized Furans to gamma-Substituted gamma -Hydroxybutenolides Using Singlet Oxygen.      

14. Stephens, B. E.; Liu, F.*
Tetrahedron Letters  2007, 48, 9116-9119.
A practical and enantiospecific conversion of D-galactose to a substituted alpha,beta-unsaturated delta-lactone synthon.    

13. Yang, M.; Liu, F.* 
Journal of Organic Chemistry  2007, 72, 8969-8971.
An Ullmann Coupling of Aryl Iodides and Amines Using an Air-Stable Diazaphospholane Ligand.

12. Patil, S. N.; Craig, D. C.; Liu, F.*
Acta Crystallographica Section E  2007, E63(6), o3021.
Benzyl 2-{(tert-butyldimethylsilyloxy)[1-(4-nitrophenyl)-2,5-dioxotetrahydro-1H-furo[3,2-d]oxazol-6a-yl]methyl}acrylate.

11. Wu, C.; Xu, Q.; Liu, F.*; Nevalainen, K. M. H. 
Biotechnology Letters  2007, 29(6), 937-943.
Activity-based Identification of Secreted Serine Proteases of the Filamentous Fungus Ophiostoma. 

10. Patil, S.N; Liu, F.*
Organic Letters  2007, 9, 193-6.
Base-assisted Regio- and Diastereoselective Conversion of Functionalized Furans to Butenolides using Singlet Oxygen.


 


From training period:
 

9. McLoughlin, S. M.; Mazur, M. T.; Miller, L. M.; Yin, J.; Liu, F.; Walsh, C. T.; Kelleher, N. L.* 
Biochemistry 2005, 14159-69.
Chemoenzymatic approaches for streamlined detection of active site modifications on thiotemplate assembly lines using mass spectrometry.

8. Yin, J., Liu, F.; Schinke, M., Daly, C, Walsh, C.T.*  
Journal of the American Chemical Society  2004, 13570-1.
Phagemid encoded small molecules for high throughput screening of chemical libraries.

7. Yin, J., Liu, F.; Li, X., Walsh, C.T.*
Journal of the American Chemical Society  2004, 7754-5.
Labeling proteins with small molecules by site-specific posttranslational modification. 

6. Liu, F. Gauneau, S.; Walsh, C.T.* 
Chemistry & Biology  2004, 1533-42.
Hybrid nonribosomal peptide-polyketide interfaces in epothilone biosynthesis: minimal requirements at N and C termini of EpoB for elongation. 

5. O’Connor, S. E.#; Walsh, C.T.*; Liu, F.# (#Equal authorship)
Angewandte Chemie International Edition  2003, 3917-21. 
Cross-System Enzyme Module Recognition for Combinatorial Biosynthesis: Linker-Dependent Interface between the Biosynthetic Pathways of Yersiniabactin and the Epothilones. 

4. Liu, F.; Johnson, E F.; Austin, D. J.; Anderson, K. S.*
Bioorganic Medicinal Chemistry Letters  2003, 3587-92.
Adenosine-Anchored Triphosphate Subsite Probing: Distinguishing between HER-2 and HER-4 Tyrosine Protein Kinases.

3. Liu, F.; Austin, D. J.*
Journal of Organic Chemistry  2001, 8643-5.
A General Synthesis of 5’-Azido-5-Deoxy-2’,3’-O-Isopropylidene Nucleosides. 

2. Liu, F.; Austin, D. J.*
Organic Letters  2001, 2273-6.
Synthesis of a New Class of 5'-Functionalized Adenosines using a Rh (II)-Catalyzed 1,3-Dipolar Cycloaddition. 

1. Liu, F.; Austin, D. J.*
Tetrahedron Letters  2001, 3153-4.
Synthesis of 5’-Functionalized Adenosine: Suppression of Cyclonucleoside Formation.